Students from the Wentzville School District competed in the High School Honors Division of Missouri’s Tri-County Regional Science and Engineering Fair held at Holt High School on Saturday, February 29. Holt junior Ethan Dunsworth received first place for his project "Exploring the Mechanisms of Major Depression and Antidepressant Response Using Gene and miRNA Expression" and will advance to the Intel International Science and Engineering Fair (ISEF) in Anaheim, California, May 10-15, 2020. Dunsworth was also awarded the Air Force Research Award and Navy Research Award for his project.

Holt senior Amaya Kopp won second place for her project "The effects of active experimental autoimmune encephalomyelitis on wild type versus transient receptor potential vanilloid 4 knockout murine central nervous systems" and earned the Air Force Research Award and Navy Research Award for her project. Holt senior Gracyn Pietrusinski won third place for her project "Characterization of H1N1 Influenza Virus Anti-Neuraminidase Specific Monoclonal Antibodies" and earned the Air Force Research Award and Navy Research Award for her project. Additionally, Holt senior Devanshi Patel won fourth place for her project "Iron catalysis in propargylic substitution reactions: solvent dependency of catalytic efficiency and catalyst decomposition studies" and will advance to the Genius Olympiad in Rochester, New York, June 15-19, 2020. Patel was also awarded the Air Force Research Award and Navy Research Award.

Holt senior Cora Sverdrup earned the American Psychological Association Award for her project "The effect of perception of musical stimuli in major and minor keys on the facilitation of artistic creative performance.” Holt junior Jacob Kampelman received the American Society of Materials Science Award for his project “Effect of Print Temperature on Shear Strength.” Timberland senior Jenna Davis received the Society of In Vitro Biology Award for her project “Determining the Effect of Caffeine Concentrations on the Heart Rate of Daphnia Magna.”